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Migalastat (1-deoxygalactonojirimycin)

Supplier:
Catalogue number:
10-2632-02
Size:
5 mg
Product is available in:
  • USA
  • Canada
$160.00 Shipping is calculated in checkout

α-galactosidase inhibitor; pharmacological chaperone. Inhibits galactosidase alpha (GLA), which interacts with SARS-CoV-2 Nsp14. Gordon et al. bioRxiv, Mar 23 2020, https://doi.org/10.1101/2020.03.22.002386.

  • Applications:Approved drug (U.S.) that could be repurposed
Product Type:

Biochemicals & reagents

CAS Number:

75172-81-5

Limit of Detection:

199.6

Storage Temperature:

-20°C

Additional Information:

Migalastat (1-deoxygalactonojirimycin) competitively inhibits alpha-galactosidase with an IC50 = 40 nM (1) and it assists with lysosomal delivery of unstable proteins and therefore is a pharmacological chaperone for treatment of lysosomal storage disorders such as Fabry disease (2).