ML300
Supplier:
Catalogue number:
10-3961-01
Size:
10 mg
Product is available in:
Protease inhibitor: SARS-CoV chymotrypsin-like protease (3CLpro, Mpro, Nsp5)
- Applications:Inhibits key SARS-CoV protease (Nsp5) that has 99% similarity overall to that of SARS-CoV-2.
Product Type:
Biochemicals & reagents
Range:
1) Turlington, et al. (2012), Non-covalent triazol-based inhibitors of the SARS main protease 3CLpro; In: Probe Reports from the NIH Molecular Libraries Program 2) Turlington et al. (2013), Discovery of N-(Benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl)carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV)3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding; Bioorg. Med. Chem. Lett. 23 6172
Limit of Detection:
431.51
Storage Temperature:
-20°C (des.)
Additional Information:
ML300 is a selective non-covalent inhibitor of SARS-CoV 3CL protease (IC50 = 4.11 µM).1,2
Related Content: