Migalastat (1-deoxygalactonojirimycin)
Supplier:
Catalogue number:
10-2632-01
Size:
1 mg
Product is available in:
$40.00
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α-galactosidase inhibitor; pharmacological chaperone. Inhibits galactosidase alpha (GLA), which interacts with SARS-CoV-2 Nsp14. Gordon et al. bioRxiv, Mar 23 2020, https://doi.org/10.1101/2020.03.22.002386.
- Applications:Approved drug (U.S.) that could be repurposed
Product Type:
Biochemicals & reagents
CAS Number:
75172-81-5
Limit of Detection:
199.6
Storage Temperature:
-20°C
Additional Information:
Migalastat (1-deoxygalactonojirimycin) competitively inhibits alpha-galactosidase with an IC50 = 40 nM (1) and it assists with lysosomal delivery of unstable proteins and therefore is a pharmacological chaperone for treatment of lysosomal storage disorders such as Fabry disease (2).