Biochemicals & reagents
1) Powers et al. (2002), Irreversible inhibitors of serine, cysteine and threonine proteases; Chem. Rev., 102 4639 2) Diatchuk et al. (1997), Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds; J. Biol. Chem., 272 13292
AEBSF HCl (30827-99-7) is an irreversible inhibitor of serine proteases including trypsin, chymotrypsin, plasmin, plasma kallikrein and thrombin. Stable, non-toxic and water-soluble alternative to PMSF1. Typical working concentrations are 0.1-1 mg/ml. AEBSF HCl may be used in cell culture or in cell lysis buffers. Inhibits NADPH oxidase activation2.