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Brefeldin A

Brefeldin A
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Size: 5 mg
$30.00
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Catalogue number:
10-1071-01
Name:
Brefeldin A
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Inhibits intracellular transport

Data sheet:

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Applications:


Inhibits intracellular transport

Product Type:
Biochemicals & reagents
CAS Number:
20350-15-6
Storage Temp:
-20°C
Molecular Weight:
280.37
Reference:
1) Fujiwara et al. (1988) Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum,; J. Biol. Chem., 263 18545 / 2) Shao et al. (1996), Brefeldin A is a potent inducer of apoptosis in human cancer cells independently of p53; Exp. Cell Res., 227 190 / 3) Linardic et al. (1996), Brefeldin A promotes hydrolysis of sphingomyelin; Cell Growth Differ. 7 765
Additional Information:
Brefeldin A (20350-15-6) is a specific inhibitor of protein translocation from endoplasmic reticulum to Golgi. Induces apoptosis. Brefeldin A activates sphingomyelin metabolism. Cell permeable.