Brefeldin A
Supplier:
Catalogue number:
10-1071-02
Size:
25 mg
Product is available in:
Inhibits intracellular transport
- Datasheet: view or download
- Applications:Inhibits intracellular transport
Product Type:
Biochemicals & reagents
CAS Number:
20350-15-6
Range:
1) Fujiwara et al. (1988) Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum,; J. Biol. Chem., 263 18545 / 2) Shao et al. (1996), Brefeldin A is a potent inducer of apoptosis in human cancer cells independently of p53; Exp. Cell Res., 227 190 / 3) Linardic et al. (1996), Brefeldin A promotes hydrolysis of sphingomyelin; Cell Growth Differ. 7 765
Limit of Detection:
280.37
Storage Temperature:
-20°C
Additional Information:
Brefeldin A (20350-15-6) is a specific inhibitor of protein translocation from endoplasmic reticulum to Golgi. Induces apoptosis. Brefeldin A activates sphingomyelin metabolism. Cell permeable.
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