Biochemicals & reagents
1) Omura et al. (1977) A new alkaloid AM-2282 of Streptomyces origin taxonomy, fermentation, isolation and preliminary characterization J. Antibiot. 30 275 / 2) Rüegg and Burgess (1989) Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. Trends in Pharmacological Science 10 218
Staurosporine (62996-74-1) is a non-selective protein kinase inhibitor with nanomolar potency. Staurosporine is widely used to induce apoptosis and to study protein kinase involvement in signal transduction pathways.