Microtubule stabilizing agent
- Datasheet: view or download
- Applications:Microtubule stabilizing agent
Product Type:
Biochemicals & reagents
CAS Number:
33069-62-4
Alternative Names:
Paclitaxel
Range:
1) Rowinsky and Donehower (1995) Drug Therapy: Paclitaxel(Taxol). N.Engl.J.Med. 332 1004 / 2) Schiff and Horwitz (1980) Taxol stabilizes microtubules in mouse fibroblast cells Proc.Nat.Acad.Sci.USA 77 1561
Limit of Detection:
853.91
Storage Temperature:
-20°C (des.)
Additional Information:
Taxol (33069-62-4) is a clinically useful cancer chemotherapeutic agent for the treatment of breast, non-small cell lung and ovarian cancer.1 Taxol acts as a promoter of tubulin polymerization and stabilizes microtubules in vitro and in vivo resulting in arrest of cells in the G2 and M phase of the cell cycle.2
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