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5-Ethynyl-2'-deoxyuridine

Supplier:
Catalogue number:
10-2794-02
Size:
250 mg
Product is available in:
  • USA
  • Canada
$140.00 Shipping is calculated in checkout

DNA labeling

Product Type:

Biochemicals & reagents

CAS Number:

61135-33-9

Alternative Names:

5-EdU

Range:

1) Salic and Mitchison (2008), A chemical method for fast and sensitive detection of DNA synthesis in vivo; Proc. Natl. Acad. Sci. USA, 105 2415 2) Zeng et al. (2010), Evaluation of 5-ethynyl-2’-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system; Brain Res., 1319C 21

Limit of Detection:

252.23

Storage Temperature:

-20°C (des.)

Additional Information:

5-Ethynyl-2'-deoxyuridine (61135-33-9) is a novel agent for fast and sensitive detection of DNA synthesis in vivo1. 5-EdU is incorporated into proliferating cells followed by detection with a fluorescent azide using click ligation1. In contrast to the use of BrdU, the new method does not require sample fixation or DNA denaturation. 5-Ethynyl-2'-deoxyuridine may be used for studying cell proliferation in the central nervous system and may be combined with BrdU staining in a novel protocol allowing for double labeling of DNA synthesis2.

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