IMP-1700
Supplier:
Catalogue number:
10-3950-01
Size:
10 mg
Product is available in:
Bacterial DNA repair inhibitor / Potent inhibitor of the bacterial DNA double-strand break repair complex AddAB. It is capable of synergistic sensitization of methicillin-resistant staphylococcus aureus (MRSA) to ciprofloxacin (EC50 = 0.6nM). IMP-1700 is an important new tool for exploring new treatment options for drug resistant bacteria.
Product Type:
Biochemicals & reagents
CAS Number:
1458674-25-3
Reference:
Lim et al. (2019), Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus; Bioorg. Med. Chem., 27 114962
Storage Temperature:
-20°C
Additional Information:
TARGET: DNA -- PATHWAY: DNA repair -- DISEASE AREA: Infectious disease