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GDC-0449

Catalogue number:
SM54-5
Size:
5 mg
Product is available in:
  • USA
  • Canada
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GDC-0449 is a potent and specific Hedgehog signaling pathway inhibitor. GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling. GDC-0449 prevents multiple ATP-binding cassette (ABC) transporters. GDC-0449 prevents the growth of primary pancreatic xenografts without non-specifically inhibiting pancreatic cell proliferation.

Product Type:

Peptides & proteins

CAS Number:

879085-55-9

Alternative Names:

Vismodegib, HhAntag691, 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide