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Fasudil Hydrochloride

Fasudil Hydrochloride
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Size: 50 mg
$155.00
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Catalogue number:
SM49-50
Name:
Fasudil Hydrochloride
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Fasudil hydrochloride is a cyclic nucleotide-dependent Rho-associated kinase inhibitor. The Rho-kinase (ROCK) mediates vasoconstriction and vascular remodeling. Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC) dissociation-induced apoptosis, increase hESC cloning efficiency and facilitate hESC subcloning after gene transfer.

Data sheet:

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Product Type:
Peptides & proteins
CAS Number:
105628-07-7
Alternative Names:
HA-1077 hydrochloride, Eril, AT-877, 5-(1,4-diazepan1-ylsulfonyl)isoquinoline hydrochloride
Storage Temp:
-20°C. Keep away from direct sunlight.
Molecular Weight:
327.83
Material Safety Data Sheet:
Reference:
1) Watanabe, K., et al. 2007. Nat Biotechnol. 25(6): 681-686. PMID: 17529971; 2) Zhang, XZ. 2010. Reprod Biomed Online. 21(1): 26-36. PMID: 20462797; 3) O, E., et al. 2011. Int J Mol Med. 28(3): 357-363. PMID: 21567077
Shelf Life:
12 months from receipt