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1 mg
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SB590885 is another selective small-molecule inhibitor of the B-Raf kinase. It has been used to overcome the dependence of MAPK signaling and tumor cell growth on BRaf kinase activity. The inhibition of MAP kinase is one of the vital ways to get rid of un-wanted tumor growth. SB590885 also act as an angiogenesis inhibitor and it helps in the research studies of different important kinase pathways. In melanoma and colorectal cancer cell lines with B-Raf V600E mutation, an effective inhibition of cell proliferation was achieved by using SB590885 at concentrations that blocked ERK phosphorylation.

Product Type:

Peptides & proteins

CAS Number:


Alternative Names:

SB 590885, SB-590885, (E)-5-(2-(4-(2-(dimethylamino)ethoxy)phenyl)-4-(pyridin-4-yl)-1Himidazol-5-yl)-2,3-dihydroinden-1-one oxime