SB203580
Supplier:
Catalogue number:
SM32-50
Size:
50 mg
Product is available in:
SB203580 is a specific inhibitor of p38-MAPK pathway. SB203580 also inhibits protein kinase B (PKB, also known as Akt) and TLR signaling pathway. SB203580 inhibits the IL-2-induced proliferation of primary human T cells, murine CT6 T cells, or BAF F7 B cells with an IC50 of 3 - 5 μM. SB203580 suppresses the development of endometriosis by down-regulating proinflammatory cytokines and proteolytic factors in a mouse model. It is a new reversal agent of P-glycoprotein-mediated multidrug resistance.
Product Type:
Peptides & proteins
CAS Number:
152121-47-6
Alternative Names:
RWJ 64809, PB 203580, 4-[4-(4-fluorophenyl)-2-[4-methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine