Pifithrin-μ
Supplier:
Catalogue number:
SM29-2.5
Size:
2.5 mg
Product is available in:
Pifithrin μ selectively interacts with HSP70 and disrupts its association with co-chaperones and substrate proteins. It induces apoptosis and it is cell permeable. Also, inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL. Pifithrin μ rescues cells from lethal γ-irradiation-induced cell death.
Product Type:
Peptides & proteins
CAS Number:
64984-31-2
Alternative Names:
PFTu, NSC 303580, PIF, 2-Phenylethynesulfonamide