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BIX01294 Trihydrochloride Hydrate 

BIX01294 Trihydrochloride Hydrate 
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Size: 2 mg
$55.00
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Catalogue number:
SM12-2
Name:
BIX01294 Trihydrochloride Hydrate 
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BIX01294 is a G9a-like protein and G9a histone lysine methyltransferase inhibitor (IC50 values are 0.7 and 1.7 μM, respectively) that displays no activity at other histone methyltransferases up to 37 μM. BIX01294 modulates H3K9me2 levels in mammalian cells and potentiates induction of pluripotent stem cells from somatic cells in-vitro.

Data sheet:

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Product Type:
Peptides & proteins
CAS Number:
1392399-03-9
Alternative Names:
BIX 01294, BIX-01294, 2-(Hexahydro-4-methyl-1H-1, 4-diazepin-1-yl)-6, 7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride
Storage Temp:
-20°C. Keep away from direct sunlight.
Molecular Weight:
600.02
Material Safety Data Sheet:
Reference:
1) Tachibana, M., et al., 2002. Genes Dev. 16(14): 1779-1791. PMID: 12130538; 2) Wagschal, A., et al. 2008. Mol Cell Biol. 28(3) 1104-1113. PMID: 18039842; 3) Thomas, L.R., et al. 2008. J Immunol. 181(1): 485-493. PMID: 18566414; 4) Kubicek, S., et al. 2007. Mol Cell. 25(3): 473-481. PMID: 17289593 5. Shi, Y., et al. 2008. Cell Stem Cell. 3(5): 568-574. PMID: 18983970
Shelf Life:
12 months from receipt