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CHIR99021 

Catalogue number:
SM13-10
Size:
10 mg
Product is available in:
  • USA
  • Canada
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CHIR99021 is an aminopyrimidine derivative. CHIR99021 inhibits GSK3 beta (IC50 = 6.7 nM) and GSK3 alpha (IC50 = 10 nM) and functions as a WNT pathway activator. CHIR99021 is widely used in definitive endoderm differentiation protocols.

Product Type:

Peptides & proteins

CAS Number:

252917-06-9

Alternative Names:

CHIR-99021, CHIR 99021, CT 99021, CHIR 911, GSK3 Inhibitor XVI, 6-​[[2-​[[4-​(2,​4-​dichlorophenyl)-​5-​(5-methyl-​1H-​imidazol-​2-​yl)-​2-pyrimidinyl]amino]ethyl]amino]-​3-​pyridinecarbonitrile

Range:

1) Naujok, O., et al. 2014. BMC Res Notes. 7(1): 273. PMID: 24779365; 2) Tsukiyama, T. and Ohinata, Y. 2014. PLoS One. 9(4): e95329. PMID: 24736627

Limit of Detection:

465.35

Storage Temperature:

-20°C. Keep away from direct sunlight.

Shelf Life:

12 months from receipt

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