Catalogue number:
GFH168-1000
Name:
SHH
Supplier:
Availability:


Recombinant Human Sonic Hedgehog is a member of a small group of secreted proteins that are essential for development in both vertebrates and invertebrates. Three mammalian hedgehog genes (sonic, desert, Indian) share about 60% homology. The Cys at position 25 has been substituted with Ile. Human SHH is a non-glycosylated polypeptide consisting of 175 amino acids with a molecular weight of 19,697 Da.
Data sheet:
Product Type:
Peptides & proteins
Alternative Names:
Shh, HHG-1
Storage Temp:
-20°C
Molecular Weight:
20.2 kDa
Specifications:
PURITY (MIN.): ≥95
UNSPSC Code:
12352202
Additional Information:
NAME: Sonic Hedgehog; ACCESSION/UNIPROT#: Q15465; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: CCL-226 cell proliferation with an acceptance criteria of 5 ug/mL (ED50), 200 units/mg.; #AA: 179; SEQUENCE: MIIGPGRGFG KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKISRNSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRALDITTS DRDRSKYGML ARLAVEAGFD WVYYESKAHI HCSVKAENSV AAKSGG

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