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BIRB796

BIRB796
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Size: 25 mg
$245.00
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Catalogue number:
SM11-25
Name:
BIRB796
Supplier:
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BIRB796 is a protein kinase inhibitor of p38 MAPK. BIRB796 has high picomolar affinity for p38 MAP kinase and low nanomolar inhibitory activity against TNF-alpha in THP-1 cell culture. The p38 inhibitor BIRB796 binds tightly to ABL(T315I) and inhibits the BMS-354825 and imatinib-resistant ABL(T315I) kinase. BIRB796 has been used as part of the naive human stem cell (NSHM) medium to create naive state human cells.

Data sheet:

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Product Type:
Peptides & proteins
CAS Number:
285983-48-4
Alternative Names:
Doramapimod, BIRB-796, BIRB 796, 285983-48-4, S1574_Selleck, Kinome_2137, 1kv2, UNIIHO1A8B3YVV, Doramapimod (USAN/INN), 1-(5-tertButyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4- yl-ethoxy)naphthalen-1-yl]urea
Storage Temp:
-20°C. Keep away from direct sunlight.
Molecular Weight:
527.66
Material Safety Data Sheet:
Reference:
1) Gafni, O., et al. 2013. Nature. 504(7479): 282-286. PMID: 24172903
Shelf Life:
12 months from receipt