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β-Pompilidotoxin

β-Pompilidotoxin
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Size: 5000 µg
$300.00
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Catalogue number:
BPX001-5000
Name:
β-Pompilidotoxin
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β-Pompilidotoxin, a voltage-gated Na(+) channel activator. β-Pompilidotoxin was isolated from the venoms of two wasps, Anoplius amariensis and Batozonellus maculifrons. This short peptide slows the inactivation of neuronal sodium channels and does not affect cardiac sodium channels.

Applications:


Sodium channel activator

Product Type:
Peptides & proteins
CAS Number:
216064-36-7
Storage Temp:
Stable at room temperature under lyophilized powder. Store at -20°C for long term storage over 2 mon
Molecular Weight:
1557.91 Da
Reference:
1) Konno K., et al. (1998) Isolation and Structure of Pompilidotoxins, Novel Peptide Neurotoxins in Solitary Wasp Venoms. Biochemical and biophysical research communications.; 2) Yokota H., et al (2001) Modulation of synaptic transmission in hippocampal CA1 neurons by a novel neurotoxin (β-pompilidotoxin) derived from wasp venom. Neuroscience Research; 3) Magloire V., et al. (2011) β-pompilidotoxin modulates spontaneous activity and persistent sodium currents in spinal networks. Neuroscience.; 4) Kinoshita E., et al. (2001) Novel Wasp Toxin Discriminates between Neuronal and Cardiac Sodium Channels. Mol. Pharmaco.
Additional Information:
AA sequence: Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu-NH2