E-4031
Supplier:
Catalogue number:
10-1213-02
Size:
25 mg
Product is available in:
Herg channel blocker / Selective hERG potassium channel blocker. Inhibits the rapid delayed-rectifier K+ current (IKr). Class III antiarrhythmic agent. Cell permeable.
Product Type:
Biochemicals & reagents
CAS Number:
113558-89-7
Reference:
Ficker et al. (2002), The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo gene (HERG) mutations ; J. Biol. Chem., 277 4989 / 2) Wettwer et al. (1991), Effects of the new class III antiarrhythmic drug E-4031 on myocardial contractility and electrophysical parameters ; J. Cardiovasc. Pharmacol., 17 480
Storage Temperature:
RT
Additional Information:
TARGET: Ion channel -- PATHWAY: Potassium channel