4,9-Anhydro-tetrodotoxin
Supplier:
Catalogue number:
10-3700-01
Size:
100 ug
Product is available in:
Selective sodium channel blocker / 4,9-Anhydrotetrodotoxin is a highly selective blocker of the Na(v1.6) sodium channel. (IC50’s: Na(v1.2) = 260 nM, Na(v1.3) = 341 nM, Na(v1.4) = 988 nM, Na(v1.5) = 11.6 µM, Na(v1.6) = 7.8 nM, Na(v1.7) = 1.27 µM, Na(v1.8) = >30 µM.).1
Product Type:
Biochemicals & reagents
CAS Number:
13072-89-4
Reference:
1) Rosker et al. (2007), The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channel; Am.J.Physiol.Cell Physiol., 293 C783.
Storage Temperature:
-20°C
Additional Information:
TARGET: Ion channel -- PATHWAY: Sodium channel