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Ambroxol HCl

Supplier:
Catalogue number:
10-2296-02
Size:
500 mg
Product is available in:
  • USA
  • Canada
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Free radical scavenger / Radical scavenger with anti-inflammatory activity. Blocks the generation of reactive oxygen species by bronchoalveolar lavage cells, Inhibits doxorubicin-induced lipid peroxidation (70 mg/kg in rat), and inhibits the release of inflammatory mediators from human leukocytes and mast cells (effective dose ~ 100 µM)

Product Type:

Biochemicals & reagents

CAS Number:

23828-92-4

Reference:

1) Teramoto et al. (1999), Effects of ambroxol on spontaneous or stimulated generation of reactive oxygen species by bronchoalveolar lavage cells harvested from patients with or without chronic obstructive pulmonary diseases; Pharmacology, 59 135 / 2) Nowak et al. (1995), Ambroxol inhibits doxorubicin-induced lipid peroxidation in heart of mice; Free Radic. Biol. Med., 19 659 / 3) Gibbs et al. (1999), Ambroxol inhibits the release of histamine, leukotrienes and cytokines from human leukocytes and mast cells.; Inflamm. Res., 48 86

Storage Temperature:

RT

Additional Information:

TARGET: Ion channel -- PATHWAY: Redox; Cation channel -- RESEARCH AREA: Oxidative stress; Neuroscience -- DISEASE AREA: Inflammation; CancerPain