TPEN
Supplier:
Catalogue number:
10-1228-02
Size:
500 mg
Product is available in:
Intracellular Zn2+ chelator / TPEN is a cell permeable metal chelator. Frequently used to study effects of zinc depletion on cellular processes.1,2
Product Type:
Biochemicals & reagents
CAS Number:
16858-02-9
Reference:
1) Chimienti et al. (2001) Role of cellular zinc in programmed cell death: temporal relationship between zinc depletion, activation of caspases and cleavage of Sp family transcription factors. Biochem.Pharmacol. 62 51 / 2) Meplan et al. (2000) Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells Oncogene 19 5227
Storage Temperature:
-20°C
Additional Information:
TARGET: Chelator -- PATHWAY: Apoptosis inducer -- RESEARCH AREA: Cell death