Aquaporin 1 inhibitor / Aquaporin-1 inhibitor (IC50 = 8.1 μM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay1.
Product Type:
Biochemicals & reagents
CAS Number:
37710-81-9
Alternative Names:
3,3’-(1,3-Phenylene)bis(2-propenoic acid)
Reference:
1) Seeliger et al. (2012), Discovery of novel human aquaporin-1 blockers; ACS Chem. Biol., 8 249
Storage Temperature:
RT
Additional Information:
TARGET: Aquaporin -- PATHWAY: Ion channels -- DISEASE AREA: Cancer