MCI-186

Name: MCI-186
Brand: Focus Biomolecules
SKU: 10-2295-02
Price: 90 GBP
Availability: InStock

Supplier:

Focus Biomolecules

Catalogue number:

10-2295-02

Size:

1 g

Product is available in:

$90.00

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Antioxidant-nonphenolic / MCI-186 is an antioxidant free radical scavenger used as a neuroprotective agent following acute brain ischemia and subsequent cerebral infarction.1,2 It also protects against MPTP-induced neurotoxicity in the Substantia Nigra.3

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Product Type:

Biochemicals & reagents

CAS Number:

89-25-8

Alternative Names:

Edaravone

Reference:

1) Watanabe et al. (1994), Protective effects of MCI-186 on cerebral ischemia:possible involvement of free radical scavenging and antioxidant actions. J.Pharmacol.Exp.Ther., 268 1597 / 2) Yoshida et al. (2006) Neuroprotective effects of edavarone:a novel free radical scavenger in cerebrovascular injury. CNS Drug Reviews 12 9 / 3) Kawasaki et al. (2007) Edavarone (3-Methyl-1-phenyl-2-pyrazolin-5-one), a Radical Scavenger, Prevents 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Neurotoxicity in the Substantia Nigra but Not the Striatum. J.Pharmacol.Exp.Ther. 322 274

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Additional Information:

TARGET: Antioxidant -- PATHWAY: Redox -- RESEARCH AREA: Neuroscience; Oxidative stress -- DISEASE AREA: Neurodegeneration; Ischemia