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GsAF-I

GsAF-I
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Size: 0.5 mg
$875.00
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Catalogue number:
12GSF001-00500
Name:
GsAF-I
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GsAF-I (also termed β-theraphotoxin-Gr1b) was originally isolated from the venom of Grammostola rosea spider. This peptide toxin is reported to block the following voltage-gated sodium channels: Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6 and Nav1.7 with respective IC50 values of 0.4, 0.6, 1.3, 0.3, 1.2 and 0.04 µM. In addition, the toxin blocks the hERG1 isoform with an IC50 value of 4.8 µM.

Product Type:
Peptides & proteins
Storage Temp:
RT
Molecular Weight:
3707.48 Da
Reference:
Elisa Redaelli, et al. (2010) Target Promiscuity and Heterogeneous Effects of Tarantula Venom Peptides Affecting Na+ and K+ Ion Channels. JBC.