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Cytochalasin D

Supplier:
Catalogue number:
10-2071-01
Size:
1 mg
Product is available in:
  • USA
  • Canada
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Disrupts actin filaments

Product Type:

Biochemicals & reagents

CAS Number:

22144-77-0

Range:

1) Goddetteand et al. (1986), Actin polymerization. The mechanism of action of cytochalasin D ; J. Biol. Chem., 261 15974 / 2) Rubtsova et al. (1998), Disruption of actin microfilaments by cytochalasin D leads to activation of p53 ; FEBS Lett., 430 353

Limit of Detection:

507.63

Storage Temperature:

-20°C (des.)

Additional Information:

Cytochalsdin D (22144-77-0) is a potent inhibitor of actin polymerization which also causes the disruption of actin filaments. More potent that cytochalasin B (10-fold) and does not inhibit monosaccharide transport across cell membranes. Disruption of actin microfilaments leads to activation of p53. Cell permeable

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