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Fasudil Hydrochloride

Catalogue number:
SM49-1000
Size:
1 g
Product is available in:
  • USA
  • Canada
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Fasudil hydrochloride is a cyclic nucleotide-dependent Rho-associated kinase inhibitor. The Rho-kinase (ROCK) mediates vasoconstriction and vascular remodeling. Fasudil effectively inhibited ISO-induced heart failure, as evaluated by biometric, hemodynamic, and histological examinations. It has been demonstrated that fasudil decrease human embryonic stem cells (hESC) dissociation-induced apoptosis, increase hESC cloning efficiency and facilitate hESC subcloning after gene transfer.

Product Type:

Peptides & proteins

CAS Number:

105628-07-7

Alternative Names:

HA-1077 hydrochloride, Eril, AT-877, 5-(1,4-diazepan1-ylsulfonyl)isoquinoline hydrochloride