life science research products, biological research products, biotechnology
Use * as wildcard:
PODS Growth Factors

IL-1 α (AF)

IL-1 α (AF)
print page
Size: 100 μg
Add to basket
Catalogue number:
IL-1 α (AF)

Interleukin-1 α (IL-1 α) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1 α signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1 α and the independently regulated IL-1 β protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.

Data sheet:

Click to view / download

Product Type:
Peptides & proteins
Alternative Names:
Interleukin-1 α, IL-1F1, IL1, FAF, BAF, LEM, LAF
Storage Temp:
Accession Number:
Molecular Weight:
18 kDa
Material Safety Data Sheet: