www.mayflowerbio.com
Sales & Support: 314-485-5210

*

IL-1 α

Catalogue number:
GFM87-1000
Size:
1 mg
Product is available in:
  • USA
  • Canada
$3935.00 Shipping is calculated in checkout

Interleukin-1 α (IL-1 α) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1 α signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1 α and the independently regulated IL-1 β protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.

Product Type:

Peptides & proteins

Alternative Names:

Interleukin-1 α, IL-1F1, IL1, FAF, BAF, LEM, LAF

Limit of Detection:

18 kDa

Storage Temperature:

-20°C

Related Content: