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TNF-α (AF)

TNF-α (AF)
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Size: 5 μg
$68.00
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Catalogue number:
GFM31AF-5
Name:
TNF-α (AF)
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Tumor Necrosis Factor α (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and Natural Killer (NK) cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.

Data sheet:

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Product Type:
Peptides & proteins
Alternative Names:
Tumor Necrosis Factor α, TNFa, TNFα, TNFSF2, cachectin, DIF, necrosin, cytotoxin, cachexin, TNF
Storage Temp:
-20°C
Accession Number:
P01375
Molecular Weight:
17.5 kDa
Material Safety Data Sheet: