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TNF-α (AF)

Catalogue number:
20 μg
Product is available in:
  • USA
  • Canada
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Tumor Necrosis Factor α (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and Natural Killer (NK) cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.

Product Type:

Peptides & proteins

Alternative Names:

Tumor Necrosis Factor α, TNFa, TNFα, TNFSF2, cachectin, DIF, necrosin, cytotoxin, cachexin, TNF

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