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Cyclosporin A (CsA)

Cyclosporin A (CsA)
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Size: 5 g
$360.00
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Catalogue number:
SM43-5000
Name:
Cyclosporin A (CsA)
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Cyclosporin A is a non-polar cyclic oligopeptide metabolite. It possesses potent immunosuppressive properties, affecting primarly T-lymphocytes. Cyclosporin A is the primary tool used to prevent rejection following solid organ and/or bone marrow transplantation. Cyclosporin A inhibits phosphatase activity of calcineurin. This small molecule also inhibits formation and opening of the mitochondrial permeability transition pore (MPTP).

Data sheet:

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Product Type:
Peptides & proteins
CAS Number:
59865-13-3
Alternative Names:
Cyclosporine, Antibiotic S 7481F1, Ciclosporin A, Ramihyphin A, CsA
Storage Temp:
-20°C. Keep away from direct sunlight.
Molecular Weight:
1202.61
Material Safety Data Sheet:
Reference:
1) Anastasia, L., et al. 2010. Cell Death Diff. 17(8): 1230-1237. PMID: 20168332; 2) Woillard, J., et al. 2014. Br J Clin Pharmacol. epub. PMID: 24698009
Shelf Life:
12 months from receipt