Cyclosporin A (CsA)
Supplier:
Catalogue number:
SM43-1000
Size:
1 g
Product is available in:
Cyclosporin A is a non-polar cyclic oligopeptide metabolite. It possesses potent immunosuppressive properties, affecting primarly T-lymphocytes. Cyclosporin A is the primary tool used to prevent rejection following solid organ and/or bone marrow transplantation. Cyclosporin A inhibits phosphatase activity of calcineurin. This small molecule also inhibits formation and opening of the mitochondrial permeability transition pore (MPTP).
- Datasheet: view or download
Product Type:
Peptides & proteins
CAS Number:
59865-13-3
Alternative Names:
Cyclosporine, Antibiotic S 7481F1, Ciclosporin A, Ramihyphin A, CsA
Range:
1) ten Berge, D., et al. 2011. Nat Cell Biol. 13(9): 1070-1075. PMID: 21841791; 2) Chen, B., et al. 2009. Nat Chem Biol. 5(2): 100-107. PMID: 19125156
Limit of Detection:
466.6
Storage Temperature:
-20°C. Keep away from direct sunlight.
Shelf Life:
12 months from receipt