GSK429286A
Supplier:
Catalogue number:
SM21-2
Size:
2 mg
Product is available in:
GSK429286A is a cell-permeable, selective Rho-associated kinase (ROCK) inhibitor, active for ROCK1 and ROCK2. GSK429286A is a more selective ROCK2 inhibitor than the widely utilized ROCK inhibitor Y-27632 as assessed on kinase-specificity panel, and does not significantly inhibit LRRK2. GSK429286A significantly inhibits rat aortic ring dilation and reduces mean arterial pressure in the spontaneously hypertensive rats (SHRs).
Product Type:
Peptides & proteins
CAS Number:
864082-47-3
Alternative Names:
GSK 429286, GSK-429286, dihydropyridone indazole, N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-(4-(trifluoromethyl)phenyl)-1,4,5,6-tetrahydropyridine-3-carboxamide
Storage Temperature:
at -20°C
Shelf Life:
at least 12 months