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Go 6983

Catalogue number:
SM20-10
Size:
10 mg
Product is available in:
  • USA
  • Canada
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Go 6983 is a protein kinase C (PKC) inhibitor. Go 6983 inhibits intracellular Ca2+ accumulation, suggesting a mechanism for its vasodilator properties. The inhibition of PKC signaling is an efficient strategy to establish and maintain pluripotent rat embryonic stem cells and to facilitate reprogramming of rat embryonic fibroblasts to rat induced pluripotent stem cells.

Product Type:

Peptides & proteins

CAS Number:

133053-19-7

Alternative Names:

Goe 6983, 1H-Pyrrole-2,5-dione, 3-[1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

Range:

1) Young, LG., et al. 2005. Cardiovasc Drug Rev. 23(3): 255-272. PMID: 16252018; 2) Chen, J., et al. 2005. Mol Pharmacol. 67(1): 152-162. PMID: 15496505; 3) Rajendran, G., et al. 2013. J Biol Chem. 288(34): 24351-24362. PMID: 23846691

Limit of Detection:

442.51

Storage Temperature:

-20°C. Keep away from direct sunlight.

Shelf Life:

12 months from receipt