DAPT is a potent and specific inhibitor of gamma-secretase. This reduces antibody levels in-vivo in plasma and cerebrospinal fluid. It blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD). DAPT causes neural cells to commit to neuronal differentiation.
- Datasheet: view or download
Product Type:
Peptides & proteins
CAS Number:
208255-80-5
Alternative Names:
N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester
Range:
1) Gafni, O., et al. 2013. Nature. 504(7479): 282-286. PMID: 24172903
Limit of Detection:
527.66
Storage Temperature:
-20°C. Keep away from direct sunlight.
Shelf Life:
12 months from receipt