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ALK5 Inhibitor II

Catalogue number:
10 mg
Product is available in:
  • USA
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SU6668 is an ATP-competitive PDGFR, Flk-1/KDR and FGFR inhibitor. It presents little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2. It does not inhibit EGFR. SU6668 inhibits proliferation of HUVEC and NIH3T3 cells in-vitro and induces >75% growth inhibition against a broad range of tumor types. SU6668 shows antiangiogenic, anti-inflammatory, antimetastatic and proapototic activity and is orally active.

Product Type:

Peptides & proteins

CAS Number:


Alternative Names:

TSU-68, Orantinib, (Z)-3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid