IL-5

Interleukin-5 (IL-5) is a hematopoietic growth factor expressed in Th2, mast cells and eosinophils. IL-5 acts through its receptor, the IL-5 receptor (IL-5R) and is involved in B cell growth and eosinophil activation. Human and mouse IL-5 are cross-reactive. Recombinant human IL-5 is a non-glycosilated homodimer containing two 116 amino acid chains and with a molecular weight of 26.6 kDa.