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HB-EGF

Catalogue number:
GFH180-10
Size:
10 μg
Product is available in:
  • USA
  • Canada
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Heparin Binding EGF-like Growth Factor (HB-EGF) is a growth factor expressed by monocytes and macrophages. HB-EGF mediates its effects via EGFR, ERBB2 and ERBB4 and has higher binding affinity to the EGFR than EGF itself. It is a mitogen for fibroblasts and smooth muscle cells, but not endothelial cells. HB-EGF is a non-glycosylated protein, containing 87 amino acids, with a molecular weight of 9.9 kDa.

Product Type:

Peptides & proteins

Alternative Names:

HBEGF, Diphtheria toxin receptor, DT-R

Limit of Detection:

9.9 kDa

Storage Temperature:

-20°C

Additional Information:

NAME: Heparin Binding EGF-like Growth Factor; ACCESSION/UNIPROT#: Q99075; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: BALB/c 3T3 cell proliferation with an acceptance criteria of 1 ng/mL (ED50), 1.0 x 10^6 units/mg.; #AA: 87; SEQUENCE: MDLQEADLDL LRVTLSSKPQ ALATPNKEEH GKRKKKGKGL GKKRDPCLRK YKDFCIHGEC KYVKELRAPS CICHPGYHGERCHGLSL

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