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IL-1 α

Catalogue number:
GFH173-1000
Size:
1 mg
Product is available in:
  • USA
  • Canada
$4380.00 Shipping is calculated in checkout

Interleukin-1 alpha (IL-1 alpha) is constitutively expressed by epithelial cells, but can also be produced by most other cells upon stimulation. IL-1 alpha and IL-1 beta are two distinct and independently regulated gene products that comprise IL-1 and signal through the Type 1 IL-1 receptor (IL-1R1). Although IL-1 alpha is cell associated and IL-1 beta is secreted, they have nearly identical biological activity in that they induce adhesion molecule expression on epithelial cells, control fever induction, and play a role in arthritis and septic shock. Signaling activated by the IL-1R1 promotes these activities through a MYD88 signaling pathway similar to those associated with Toll receptors. Recombinant human IL-1 alpha is a non-glycosylated single chain protein.

Product Type:

Peptides & proteins

Alternative Names:

IL-1F1, FAF, BAF, LEM, LAF

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