Human Thymic Stromal Lymphopoietin (H-TSLP) is produced in several tissues including heart, liver and prostate. TSLP shares similar biological activities to IL-7 including enhancement of STAT3 and STAT5. TSLP induces the release of T-cell chemokines from monocytes and affects increased growth of dendritic cells. H-TSLP is also signals through the IL-7 receptor and TSLP-R receptor pathways.
Peptides & proteins
NAME: Thymic Stromal Lymphopoietin; ACCESSION/UNIPROT#: Q969D9; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; #AA: 132; SEQUENCE: MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGL WRRFNRPLL KQQ