TSLP

Human Thymic Stromal Lymphopoietin (H-TSLP) is produced in several tissues including heart, liver and prostate. TSLP shares similar biological activities to IL-7 including enhancement of STAT3 and STAT5. TSLP induces the release of T-cell chemokines from monocytes and affects increased growth of dendritic cells. H-TSLP is also signals through the IL-7 receptor and TSLP-R receptor pathways.