Recombinant Human Galectin-3 is a member of a large family of carbohydrate-binding proteins. Also known as Mac-2, L29 and CBP35, Human Galectin-3 is expressed by a wide range of cell types including activated T- cells, tumor cells, macrophages, osteoclasts, fibroblasts and epithelial cells. Galectin-3 exhibits proinflammatory activities both in vitro and in vivo. Galectin-3 also chemoattracts monocytes and macrophages. Increased circulating levels of Galectin-3 correlate with several types of cancer, suggesting Galectin -3 is involved in tumor growth and metastasis. Human and Mouse Galectin-3 share 80% homology by amino acid sequence. Human Galectin-3 is a recombinant polypeptide chain.
Peptides & proteins
Galactose-specific lectin-3, IgE-binding protein, MAC2, L-29 CPB-35
NAME: Galectin-3; ACCESSION/UNIPROT#: P17931; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50mM sodium chloride, pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; #AA: 250; SEQUENCE: MADNFSLHDA LSGSGNPNPQ GWPGAWGNQP AGAGGYPGAS YPGAYPGQAP PGAYPGQAPP GAYHGAPGAY PGAPAPGVYP GPPSGPGAYPSSGQPSAPGA YPATGPYGAP AGPLIVPYNL PLPGGVVPRM LITILGTVKP NANRIALDFQ RGNDVAFHFN PRFNENNRRV IVCNTKLDNN WGREERQSVF PFESGKPFKIQVLVEPDHFK VAVNDAHLLQ YNHRVKKLNE ISKLGISGDI DLTSASYTMI