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MIF

Catalogue number:
GFH153-5
Size:
5 μg
Product is available in:
  • USA
  • Canada
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Recombinant Human MIF (migration inhibitory factor) acts as an inflammatory mediator consisting of two alpha-helices and six beta-strands, four of which form a beta-sheet structure. The remaining two beta-strands interact with other MIF molecules forming a trimer in solution. Human MIF acts on fibroblasts by inducing IL-1, IL-8 and MMP expression. MIF stimulates NO production and TNF-alpha release following IFN-gamma activation on macrophages. Human MIF is a non-glycosylated polypeptide.

Product Type:

Peptides & proteins

Alternative Names:

MIF

Limit of Detection:

12.5 kDa

Storage Temperature:

-20°C

Additional Information:

NAME: Migration Inhibitory Factor; ACCESSION/UNIPROT#: P14174; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; #AA: 115; SEQUENCE: MPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF GGSSEPCALC SLHSIGKIGG AQNRSYSKLL CGLLAERLRI SPDRVYINYY DMNAANVGWN NSTFA

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