Macrophage Inflammatory Protein-3 alpha (MIP-3 alpha), also called CCL20, is expressed in the liver, lungs, lymph nodes and peripheral blood lymphocytes. MIP-3 alpha is strongly up regulated by inflammatory signals, and down regulated by the anti-inflammatory cytokine IL-10. MIP3 alpha signals through the G protein-coupled receptor, CCR6, and acts as a chemoattractant to lymphocytes anddendritic cells. Recombinant human MIP-3 alpha is a non-glycosylated protein.
Peptides & proteins
CCL20, Exodus-1, LARC
NAME: Macrophage Inflammatory Protein-3 alpha; ACCESSION/UNIPROT#: P78556; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; #AA: 70; SEQUENCE: ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM