A single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of angiogenesis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor. Recombinant Human FGF-2 is a single, non-glycosylated, polypeptide chain.
Peptides & proteins
FGF2, HBGF-2, Prostatropin
NAME: Fibroblast Growth Factor basic 154; ACCESSION/UNIPROT#: P09038; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 75 mM sodium chloride, pH 7.5 . Reconstitute in sterile water at 0.1 mg/mL.; TESTING: 3T3 cell proliferation with an acceptance criteria of 5 ng/mL (ED50), 2 x 10^5 units/mg.; #AA: 155; SEQUENCE: MAAGSITTLP ALPEDGGSGA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHI KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTDE CFFFERLESN NYNTYRSRKY TSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS