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Myostatin Propeptide

Catalogue number:
GFH142-100
Size:
100 μg
Product is available in:
  • USA
  • Canada
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Myostatin (GDF-8), a member of the TGF-beta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70%) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo.

Product Type:

Peptides & proteins

Alternative Names:

Myostatin Propeptide

Limit of Detection:

27.8 kDa

Storage Temperature:

-20°C

Additional Information:

NAME: Myostatin Propeptide; ACCESSION/UNIPROT#: O14793(24-266); EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile 20 mM HCI at 0.1 mg/mL.; #AA: 244; SEQUENCE: MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR

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