Macrophage Inflammatory Protein-3 beta (MIP-3 beta), also called CCL19, is a chemokine that is expressed in the thymus, lymph nodes and activated bone marrow stromal cells. MIP-3 beta signals through the G protein-coupled receptor, CCR7, to regulate normal lymphocyte recirculation and homing of T and B cells to the lymph nodes. Human MIP-3 beta shows activity on mouse cells. Recombinant human MIP-3 beta is a non-glycosylated protein.
Peptides & proteins
CCL19, SCYA19, ELC, Exodus-3
NAME: Macrophage Inflammatory Protein-3 beta; ACCESSION/UNIPROT#: Q99731; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; #AA: 77; SEQUENCE: GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS